Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 391.9 BDBM363897

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM363897 (2-[(exo)-8-(tert-Butylcarbamoyl)methyl-8-azabicycl...) Show SMILES CC(C)(C)NC(=O)CN1[C@H]2CC[C@@H]1C[C@@H](CC(=O)Nc1cccc(Cl)c1)C2 |r,THB:7:8:13.14.26:10.11| Show InChI InChI=1S/C21H30ClN3O2/c1-21(2,3)24-20(27)13-25-17-7-8-18(25)10-14(9-17)11-19(26)23-16-6-4-5-15(22)12-16/h4-6,12,14,17-18H,7-11,13H2,1-3H3,(H,23,26)(H,24,27)/t14-,17-,18+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair