Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 579.6 BDBM275019

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM275019 (N-(tert-butyl)-8-(2-phenylpiperidine-1- carbonyl)-...) Show SMILES CC(C)(C)NC(=O)N1CCc2c(C1)c(ccc2-c1cccc(OC(F)(F)F)c1)C(=O)N1CCCCC1c1ccccc1 Show InChI InChI=1S/C33H36F3N3O3/c1-32(2,3)37-31(41)38-19-17-26-25(23-12-9-13-24(20-23)42-33(34,35)36)15-16-27(28(26)21-38)30(40)39-18-8-7-14-29(39)22-10-5-4-6-11-22/h4-6,9-13,15-16,20,29H,7-8,14,17-19,21H2,1-3H3,(H,37,41)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.76E+3	n/a	n/a	n/a	n/a	7.0	25
Merck Sharp & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9877957 (2018) BindingDB Entry DOI: 10.7270/Q2Z60R2C
					More data for this Ligand-Target Pair