Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM302579
(N5-(tert-Butyl)-2-(1H-pyrazol-4- yl)-6,7-dihydropy...)Show SMILES CC(C)(C)NC(=O)N1CCn2nc(-c3cn[nH]c3)c(C(N)=O)c2C1 Show InChI InChI=1S/C15H21N7O2/c1-15(2,3)19-14(24)21-4-5-22-10(8-21)11(13(16)23)12(20-22)9-6-17-18-7-9/h6-7H,4-5,8H2,1-3H3,(H2,16,23)(H,17,18)(H,19,24) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst... |
US Patent US9598423 (2017)
BindingDB Entry DOI: 10.7270/Q2FJ2JT9 |
More data for this Ligand-Target Pair | |
Casein kinase I isoform epsilon
(Homo sapiens (Human)) | BDBM302579
(N5-(tert-Butyl)-2-(1H-pyrazol-4- yl)-6,7-dihydropy...)Show SMILES CC(C)(C)NC(=O)N1CCn2nc(-c3cn[nH]c3)c(C(N)=O)c2C1 Show InChI InChI=1S/C15H21N7O2/c1-15(2,3)19-14(24)21-4-5-22-10(8-21)11(13(16)23)12(20-22)9-6-17-18-7-9/h6-7H,4-5,8H2,1-3H3,(H2,16,23)(H,17,18)(H,19,24) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst... |
US Patent US9598423 (2017)
BindingDB Entry DOI: 10.7270/Q2FJ2JT9 |
More data for this Ligand-Target Pair | |