Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Beta-secretase 1
(Homo sapiens (Human)) | BDBM314910
(US9611261, Example 433)Show SMILES CC(C)(C)OC(=O)N=C1OC2C[C@@H]2[C@](CF)(N1C(=O)OC(C)(C)C)c1cc(c(CO)cc1F)-c1cncc(F)c1 |r| Show InChI InChI=1S/C28H32F3N3O6/c1-26(2,3)39-24(36)33-23-34(25(37)40-27(4,5)6)28(14-29,20-10-22(20)38-23)19-9-18(16(13-35)8-21(19)31)15-7-17(30)12-32-11-15/h7-9,11-12,20,22,35H,10,13-14H2,1-6H3/t20-,22?,28+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 2.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
US Patent
| Assay Description
The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic... |
US Patent US9611261 (2017)
BindingDB Entry DOI: 10.7270/Q21J9CW2 |
More data for this
Ligand-Target Pair | |
Cathepsin D
(Homo sapiens (Human)) | BDBM314910
(US9611261, Example 433)Show SMILES CC(C)(C)OC(=O)N=C1OC2C[C@@H]2[C@](CF)(N1C(=O)OC(C)(C)C)c1cc(c(CO)cc1F)-c1cncc(F)c1 |r| Show InChI InChI=1S/C28H32F3N3O6/c1-26(2,3)39-24(36)33-23-34(25(37)40-27(4,5)6)28(14-29,20-10-22(20)38-23)19-9-18(16(13-35)8-21(19)31)15-7-17(30)12-32-11-15/h7-9,11-12,20,22,35H,10,13-14H2,1-6H3/t20-,22?,28+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 6.13E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
US Patent
| Assay Description
Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ... |
US Patent US9611261 (2017)
BindingDB Entry DOI: 10.7270/Q21J9CW2 |
More data for this
Ligand-Target Pair | |