Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50159707
(CHEMBL3786152)Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)[C@@H]1Cc2ccccc2CN1C(=O)CCCC(=O)c1ccccc1)C(=O)NCC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C46H54N4O6/c1-46(2,3)56-45(55)49-39(43(53)48-31-38(33-18-7-4-8-19-33)34-20-9-5-10-21-34)26-15-16-29-47-44(54)40-30-36-24-13-14-25-37(36)32-50(40)42(52)28-17-27-41(51)35-22-11-6-12-23-35/h4-14,18-25,38-40H,15-17,26-32H2,1-3H3,(H,47,54)(H,48,53)(H,49,55)/t39-,40-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 166 | n/a | n/a | n/a | n/a |
Friedrich Alexander University
Curated by ChEMBL
| Assay Description Positive allosteric modulation of ProLink2-tagged wild type CXCR3 (unknown origin) expressed in HEK293T cells assessed as beta-arrestin-2 recruitment... |
J Med Chem 59: 2222-43 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01965 BindingDB Entry DOI: 10.7270/Q2T72KBR |
More data for this Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50159707
(CHEMBL3786152)Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)[C@@H]1Cc2ccccc2CN1C(=O)CCCC(=O)c1ccccc1)C(=O)NCC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C46H54N4O6/c1-46(2,3)56-45(55)49-39(43(53)48-31-38(33-18-7-4-8-19-33)34-20-9-5-10-21-34)26-15-16-29-47-44(54)40-30-36-24-13-14-25-37(36)32-50(40)42(52)28-17-27-41(51)35-22-11-6-12-23-35/h4-14,18-25,38-40H,15-17,26-32H2,1-3H3,(H,47,54)(H,48,53)(H,49,55)/t39-,40-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 145 | n/a | n/a | n/a | n/a |
Friedrich Alexander University
Curated by ChEMBL
| Assay Description Positive allosteric modulation of ProLink1-tagged wild type CXCR3 (unknown origin) expressed in HEK293T cells assessed as beta-arrestin-2 recruitment... |
J Med Chem 59: 2222-43 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01965 BindingDB Entry DOI: 10.7270/Q2T72KBR |
More data for this Ligand-Target Pair | |