Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50159706
(CHEMBL3787609)Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)[C@@H]1Cc2ccccc2CN1C(=O)CCc1ccccc1)C(=O)NCC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C44H52N4O5/c1-44(2,3)53-43(52)47-38(41(50)46-30-37(33-19-9-5-10-20-33)34-21-11-6-12-22-34)25-15-16-28-45-42(51)39-29-35-23-13-14-24-36(35)31-48(39)40(49)27-26-32-17-7-4-8-18-32/h4-14,17-24,37-39H,15-16,25-31H2,1-3H3,(H,45,51)(H,46,50)(H,47,52)/t38-,39-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 62 | n/a | n/a | n/a | n/a |
Friedrich Alexander University
Curated by ChEMBL
| Assay Description Positive allosteric modulation of ProLink1-tagged wild type CXCR3 (unknown origin) expressed in HEK293T cells assessed as beta-arrestin-2 recruitment... |
J Med Chem 59: 2222-43 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01965 BindingDB Entry DOI: 10.7270/Q2T72KBR |
More data for this Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50159706
(CHEMBL3787609)Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)[C@@H]1Cc2ccccc2CN1C(=O)CCc1ccccc1)C(=O)NCC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C44H52N4O5/c1-44(2,3)53-43(52)47-38(41(50)46-30-37(33-19-9-5-10-20-33)34-21-11-6-12-22-34)25-15-16-28-45-42(51)39-29-35-23-13-14-24-36(35)31-48(39)40(49)27-26-32-17-7-4-8-18-32/h4-14,17-24,37-39H,15-16,25-31H2,1-3H3,(H,45,51)(H,46,50)(H,47,52)/t38-,39-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 195 | n/a | n/a | n/a | n/a |
Friedrich Alexander University
Curated by ChEMBL
| Assay Description Positive allosteric modulation of ProLink2-tagged wild type CXCR3 (unknown origin) expressed in HEK293T cells assessed as beta-arrestin-2 recruitment... |
J Med Chem 59: 2222-43 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01965 BindingDB Entry DOI: 10.7270/Q2T72KBR |
More data for this Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50159706
(CHEMBL3787609)Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)[C@@H]1Cc2ccccc2CN1C(=O)CCc1ccccc1)C(=O)NCC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C44H52N4O5/c1-44(2,3)53-43(52)47-38(41(50)46-30-37(33-19-9-5-10-20-33)34-21-11-6-12-22-34)25-15-16-28-45-42(51)39-29-35-23-13-14-24-36(35)31-48(39)40(49)27-26-32-17-7-4-8-18-32/h4-14,17-24,37-39H,15-16,25-31H2,1-3H3,(H,45,51)(H,46,50)(H,47,52)/t38-,39-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 61.7 | n/a | n/a | n/a | n/a |
Friedrich Alexander University
Curated by ChEMBL
| Assay Description Positive allosteric modulation of ProLink1-tagged wild type CXCR3 (unknown origin) expressed in HEK293T cells assessed as beta-arrestin-2 recruitment... |
J Med Chem 59: 2222-43 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01965 BindingDB Entry DOI: 10.7270/Q2T72KBR |
More data for this Ligand-Target Pair | |