Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 593.5 BDBM50364396

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50364396 (CHEMBL1950455) Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N1CCCC[C@H]1c1nc2cc(Cl)c(Cl)cc2[nH]1 |r| Show InChI InChI=1S/C32H34Cl2N4O3/c1-32(2,3)41-31(40)37-27(17-20-12-14-22(15-13-20)21-9-5-4-6-10-21)30(39)38-16-8-7-11-28(38)29-35-25-18-23(33)24(34)19-26(25)36-29/h4-6,9-10,12-15,18-19,27-28H,7-8,11,16-17H2,1-3H3,(H,35,36)(H,37,40)/t27-,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate for 30 mins by continuous fluorimetric assay				Bioorg Med Chem Lett 22: 1774-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.064 BindingDB Entry DOI: 10.7270/Q27H1K28
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