Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 527.4 BDBM360607

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360607 (US9828369, Example 165 | tert-butyl 3-(8-((3-(2,3-...) Show SMILES CC(C)(C)OC(=O)N1CCC=C(C1)c1ccc(CNC(=O)Nc2cccc(Cl)c2Cl)c2cnccc12 |c:10| Show InChI InChI=1S/C27H28Cl2N4O3/c1-27(2,3)36-26(35)33-13-5-6-18(16-33)19-10-9-17(21-15-30-12-11-20(19)21)14-31-25(34)32-23-8-4-7-22(28)24(23)29/h4,6-12,15H,5,13-14,16H2,1-3H3,(H2,31,32,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair