Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 629.2 BDBM50304905

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM50304905 ((R)-3-(5-((1-(tert-butoxycarbonyl)pyrrolidin-2-yl)...) Show SMILES CC(C)(C)OC(=O)N1CCC[C@@H]1COc1ccc2n(Cc3ccc(Cl)cc3)c(CC(C)(C)C(O)=O)c(SC(C)(C)C)c2c1 |r| Show InChI InChI=1S/C34H45ClN2O5S/c1-32(2,3)42-31(40)36-17-9-10-24(36)21-41-25-15-16-27-26(18-25)29(43-33(4,5)6)28(19-34(7,8)30(38)39)37(27)20-22-11-13-23(35)14-12-22/h11-16,18,24H,9-10,17,19-21H2,1-8H3,(H,38,39)/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amira Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to FLAP in human PMN derived membrane				Bioorg Med Chem Lett 20: 213-7 (2010) Article DOI: 10.1016/j.bmcl.2009.10.131 BindingDB Entry DOI: 10.7270/Q2MW2H78
					More data for this Ligand-Target Pair