Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 532.6 BDBM50584703

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NT-3 growth factor receptor (Homo sapiens (Human))	BDBM50584703 (CHEMBL5076205) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Nc3ncnc4NC(=O)C(C)(C)Oc34)cc2)n(n1)C1CCCCC1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild type TrkC (unknown origin) using poly(Glu: Tyr) as substrate preincubated for 15 mins followed by substrate addition and further i...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01597 BindingDB Entry DOI: 10.7270/Q2377DMN
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM50584703 (CHEMBL5076205) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Nc3ncnc4NC(=O)C(C)(C)Oc34)cc2)n(n1)C1CCCCC1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild type TrkB (unknown origin) using poly(Glu: Tyr) as substrate preincubated for 15 mins followed by substrate addition and further i...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01597 BindingDB Entry DOI: 10.7270/Q2377DMN
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50584703 (CHEMBL5076205) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Nc3ncnc4NC(=O)C(C)(C)Oc34)cc2)n(n1)C1CCCCC1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	344	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild type TrkA (unknown origin) using poly(Glu: Tyr) as substrate preincubated for 15 mins followed by substrate addition and further i...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01597 BindingDB Entry DOI: 10.7270/Q2377DMN
					More data for this Ligand-Target Pair