Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 411.4 BDBM509775

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Anoctamin-1 (Homo sapiens (Human))	BDBM509775 (US11364246, Example 93.2 | US20200361871A1, Exampl...) Show SMILES CC(C)(C)c1ccc(CC(=O)Nc2ccnc(c2)C(=O)NC2CCC[C@@H]2O)cc1O |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
TBA					Assay Description Cell Culture and PreparationFisher rat thyroid (FRT) cells stably expressing human TMEM16A (TMEM16Aabc variant; Dr Luis Galietta, Insituto Giannina, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KW5K8C
					More data for this Ligand-Target Pair
Anoctamin-1 (Homo sapiens (Human))	BDBM509775 (US11364246, Example 93.2 | US20200361871A1, Exampl...) Show SMILES CC(C)(C)c1ccc(CC(=O)Nc2ccnc(c2)C(=O)NC2CCC[C@@H]2O)cc1O |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
TBA					Assay Description Compound activity was quantified by measuring the increase in current upon compound addition and expressing this as a percentage increase of baseline...				Citation and Details BindingDB Entry DOI: 10.7270/Q2M32ZXP
					More data for this Ligand-Target Pair