Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 266.3 BDBM50394735

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50394735 (CHEMBL2165810) Show SMILES CC(C)(C)c1ccc(cc1)-c1cnc2ccnn2c1N Show InChI InChI=1S/C16H18N4/c1-16(2,3)12-6-4-11(5-7-12)13-10-18-14-8-9-19-20(14)15(13)17/h4-10H,17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...				J Med Chem 55: 1751-7 (2012) Article DOI: 10.1021/jm201524g BindingDB Entry DOI: 10.7270/Q2862HJ9
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