Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 442.5 BDBM150231

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM150231 (US8980916, 6) Show SMILES CC(C)(C)c1ccc(cc1)-n1cccc(C(O)C(=O)Nc2ccc3c(N)nccc3c2)c1=O Show InChI InChI=1S/C26H26N4O3/c1-26(2,3)17-6-9-19(10-7-17)30-14-4-5-21(25(30)33)22(31)24(32)29-18-8-11-20-16(15-18)12-13-28-23(20)27/h4-15,22,31H,1-3H3,(H2,27,28)(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	54	n/a	n/a	n/a	n/a	8.0	25
Merck Sharp & Dohme Corp.; Mochida Pharmaceutical Co., Ltd. US Patent					Assay Description Inhibitory activity against Factor IXa was tested using the substrate SPECTROFLUOR FIXa (American Diagnostica Inc.; 500 West Avenue, Stamford, Conn. ...				US Patent US8980916 (2015) BindingDB Entry DOI: 10.7270/Q2RB739T
					More data for this Ligand-Target Pair