Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human)) | BDBM50272119
(CHEMBL4130328)Show SMILES CC(C)(CC(O)=O)C#Cc1ccc(cc1)N1CCOc2ncnc(N)c2C1=O Show InChI InChI=1S/C20H20N4O4/c1-20(2,11-15(25)26)8-7-13-3-5-14(6-4-13)24-9-10-28-18-16(19(24)27)17(21)22-12-23-18/h3-6,12H,9-11H2,1-2H3,(H,25,26)(H2,21,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 281 | n/a | n/a | n/a | n/a | n/a | n/a |
WuXi AppTec (Shanghai) Co. Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ... |
Bioorg Med Chem Lett 28: 1686-1692 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.051
BindingDB Entry DOI: 10.7270/Q2K64MKJ |
More data for this
Ligand-Target Pair | |
Diacylglycerol O-acyltransferase 1
(Mus musculus (mouse)) | BDBM50272119
(CHEMBL4130328)Show SMILES CC(C)(CC(O)=O)C#Cc1ccc(cc1)N1CCOc2ncnc(N)c2C1=O Show InChI InChI=1S/C20H20N4O4/c1-20(2,11-15(25)26)8-7-13-3-5-14(6-4-13)24-9-10-28-18-16(19(24)27)17(21)22-12-23-18/h3-6,12H,9-11H2,1-2H3,(H,25,26)(H2,21,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 282 | n/a | n/a | n/a | n/a | n/a | n/a |
WuXi AppTec (Shanghai) Co. Ltd
Curated by ChEMBL
| Assay Description
Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ... |
Bioorg Med Chem Lett 28: 1686-1692 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.051
BindingDB Entry DOI: 10.7270/Q2K64MKJ |
More data for this
Ligand-Target Pair | |