Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cysteinyl leukotriene receptor 1
(GUINEA PIG) | BDBM50084797
(4-(2-methyl-1-(7-(quinolin-2-ylmethoxy)naphthalene...)Show SMILES CC(C)(CNS(=O)(=O)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C31H28N2O5S/c1-31(2,25-12-7-23(8-13-25)30(34)35)20-32-39(36,37)28-16-11-21-10-15-27(17-24(21)18-28)38-19-26-14-9-22-5-3-4-6-29(22)33-26/h3-18,32H,19-20H2,1-2H3,(H,34,35) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratorios Menarini
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes |
J Med Chem 43: 392-400 (2000)
BindingDB Entry DOI: 10.7270/Q2DJ5DVX |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50084797
(4-(2-methyl-1-(7-(quinolin-2-ylmethoxy)naphthalene...)Show SMILES CC(C)(CNS(=O)(=O)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C31H28N2O5S/c1-31(2,25-12-7-23(8-13-25)30(34)35)20-32-39(36,37)28-16-11-21-10-15-27(17-24(21)18-28)38-19-26-14-9-22-5-3-4-6-29(22)33-26/h3-18,32H,19-20H2,1-2H3,(H,34,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang University
Curated by ChEMBL
| Assay Description
Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L... |
Bioorg Med Chem 18: 5519-27 (2010)
Article DOI: 10.1016/j.bmc.2010.06.047
BindingDB Entry DOI: 10.7270/Q26D5TZ0 |
More data for this
Ligand-Target Pair | |