Found 4 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Calcium-dependent protein kinase 1
(Cryptosporidium parvum) | BDBM286287
(US9518026, Example 80 | US9956214, Compound 1644)Show SMILES CC(C)(CO)Cn1nc(c(C(N)=O)c1N)-c1cnc2cc(OC3CCC3)ccc2c1 Show InChI InChI=1S/C22H27N5O3/c1-22(2,12-28)11-27-20(23)18(21(24)29)19(26-27)14-8-13-6-7-16(9-17(13)25-10-14)30-15-4-3-5-15/h6-10,15,28H,3-5,11-12,23H2,1-2H3,(H2,24,29) | UniProtKB/TrEMBL
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim (Canada) Ltd.
| Assay Description
Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
Bioorg Med Chem Lett 19: 1199-205 (2009)
BindingDB Entry DOI: 10.7270/Q23J3G91 |
More data for this
Ligand-Target Pair | |
Uncharacterized protein
(Cryptosporidium parvum) | BDBM286287
(US9518026, Example 80 | US9956214, Compound 1644)Show SMILES CC(C)(CO)Cn1nc(c(C(N)=O)c1N)-c1cnc2cc(OC3CCC3)ccc2c1 Show InChI InChI=1S/C22H27N5O3/c1-22(2,12-28)11-27-20(23)18(21(24)29)19(26-27)14-8-13-6-7-16(9-17(13)25-10-14)30-15-4-3-5-15/h6-10,15,28H,3-5,11-12,23H2,1-2H3,(H2,24,29) | PDB
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Through its Center For Commercialization
US Patent
| Assay Description
Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
US Patent US9518026 (2016)
BindingDB Entry DOI: 10.7270/Q2BV7JN4 |
More data for this
Ligand-Target Pair | |
Calmodulin-domain protein kinase 1
(Toxoplasma gondii) | BDBM286287
(US9518026, Example 80 | US9956214, Compound 1644)Show SMILES CC(C)(CO)Cn1nc(c(C(N)=O)c1N)-c1cnc2cc(OC3CCC3)ccc2c1 Show InChI InChI=1S/C22H27N5O3/c1-22(2,12-28)11-27-20(23)18(21(24)29)19(26-27)14-8-13-6-7-16(9-17(13)25-10-14)30-15-4-3-5-15/h6-10,15,28H,3-5,11-12,23H2,1-2H3,(H2,24,29) | PDB
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim (Canada) Ltd.
| Assay Description
Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
Bioorg Med Chem Lett 19: 1199-205 (2009)
BindingDB Entry DOI: 10.7270/Q23J3G91 |
More data for this
Ligand-Target Pair | |
Calmodulin-domain protein kinase 1
(Toxoplasma gondii) | BDBM286287
(US9518026, Example 80 | US9956214, Compound 1644)Show SMILES CC(C)(CO)Cn1nc(c(C(N)=O)c1N)-c1cnc2cc(OC3CCC3)ccc2c1 Show InChI InChI=1S/C22H27N5O3/c1-22(2,12-28)11-27-20(23)18(21(24)29)19(26-27)14-8-13-6-7-16(9-17(13)25-10-14)30-15-4-3-5-15/h6-10,15,28H,3-5,11-12,23H2,1-2H3,(H2,24,29) | PDB
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Through its Center For Commercialization
US Patent
| Assay Description
Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
US Patent US9518026 (2016)
BindingDB Entry DOI: 10.7270/Q2BV7JN4 |
More data for this
Ligand-Target Pair | |