Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human)) | BDBM165172
(US9067917, 207 | US9682971, 207)Show SMILES CC(C)(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(cc1)-n1nccn1)C(O)=O Show InChI InChI=1S/C31H28N6O3/c1-31(2,30(38)39)18-29-35-27-17-25(40-20-23-10-9-22-5-3-4-6-26(22)34-23)13-14-28(27)36(29)19-21-7-11-24(12-8-21)37-32-15-16-33-37/h3-17H,18-20H2,1-2H3,(H,38,39) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| 620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
JANSSEN PHARMACEUTICA NV
US Patent
| Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai... |
US Patent US9682971 (2017)
BindingDB Entry DOI: 10.7270/Q2P26W84 |
More data for this
Ligand-Target Pair | |
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human)) | BDBM165172
(US9067917, 207 | US9682971, 207)Show SMILES CC(C)(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(cc1)-n1nccn1)C(O)=O Show InChI InChI=1S/C31H28N6O3/c1-31(2,30(38)39)18-29-35-27-17-25(40-20-23-10-9-22-5-3-4-6-26(22)34-23)13-14-28(27)36(29)19-21-7-11-24(12-8-21)37-32-15-16-33-37/h3-17H,18-20H2,1-2H3,(H,38,39) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| 620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV
US Patent
| Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai... |
US Patent US9067917 (2015)
BindingDB Entry DOI: 10.7270/Q24748M5 |
More data for this
Ligand-Target Pair | |