Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 607.4 BDBM50365018

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50365018 (CHEMBL1950786) Show SMILES CC(C)(N)C(=O)Nc1cc(cnc1N1CCC[C@H]1c1nc2cc(Cl)c(Cl)cc2[nH]1)-c1ccc(OCC(F)(F)F)cc1 |r| Show InChI InChI=1S/C28H27Cl2F3N6O2/c1-27(2,34)26(40)38-22-10-16(15-5-7-17(8-6-15)41-14-28(31,32)33)13-35-25(22)39-9-3-4-23(39)24-36-20-11-18(29)19(30)12-21(20)37-24/h5-8,10-13,23H,3-4,9,14,34H2,1-2H3,(H,36,37)(H,38,40)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate after 30 mins by fluorescence analysis				Bioorg Med Chem Lett 22: 1727-30 (2012) Article DOI: 10.1016/j.bmcl.2011.12.098 BindingDB Entry DOI: 10.7270/Q2GT5NNH
					More data for this Ligand-Target Pair