Found 6 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Matrix protein 2
(Influenza A virus (A/Udorn/307/1972(H3N2))) | BDBM50465108
(CHEMBL4277543)Show SMILES CC(C)(N)C12CC3CC(CC(C3)C1)C2 |TLB:7:8:12:5.6.11,THB:7:6:12:13.8.9,9:8:5:12.10.11,9:10:5:13.8.7| Show InChI InChI=1S/C13H23N/c1-12(2,14)13-6-9-3-10(7-13)5-11(4-9)8-13/h9-11H,3-8,14H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National and Kapodistrian University of Athens
Curated by ChEMBL
| Assay Description Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes assessed as blockade of inward currents at... |
ACS Med Chem Lett 9: 198-203 (2018)
Article DOI: 10.1021/acsmedchemlett.7b00458 BindingDB Entry DOI: 10.7270/Q2GQ71F3 |
More data for this Ligand-Target Pair | |
Matrix protein 2
(Influenza A virus (A/Udorn/307/1972(H3N2))) | BDBM50465108
(CHEMBL4277543)Show SMILES CC(C)(N)C12CC3CC(CC(C3)C1)C2 |TLB:7:8:12:5.6.11,THB:7:6:12:13.8.9,9:8:5:12.10.11,9:10:5:13.8.7| Show InChI InChI=1S/C13H23N/c1-12(2,14)13-6-9-3-10(7-13)5-11(4-9)8-13/h9-11H,3-8,14H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National and Kapodistrian University of Athens
Curated by ChEMBL
| Assay Description Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes assessed as blockade of inward currents at... |
ACS Med Chem Lett 9: 198-203 (2018)
Article DOI: 10.1021/acsmedchemlett.7b00458 BindingDB Entry DOI: 10.7270/Q2GQ71F3 |
More data for this Ligand-Target Pair | |
Matrix protein 2
(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...) | BDBM50465108
(CHEMBL4277543)Show SMILES CC(C)(N)C12CC3CC(CC(C3)C1)C2 |TLB:7:8:12:5.6.11,THB:7:6:12:13.8.9,9:8:5:12.10.11,9:10:5:13.8.7| Show InChI InChI=1S/C13H23N/c1-12(2,14)13-6-9-3-10(7-13)5-11(4-9)8-13/h9-11H,3-8,14H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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PC cid PC sid UniChem
| | n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Matrix protein 2
(Influenza A virus (A/Udorn/307/1972(H3N2))) | BDBM50465108
(CHEMBL4277543)Show SMILES CC(C)(N)C12CC3CC(CC(C3)C1)C2 |TLB:7:8:12:5.6.11,THB:7:6:12:13.8.9,9:8:5:12.10.11,9:10:5:13.8.7| Show InChI InChI=1S/C13H23N/c1-12(2,14)13-6-9-3-10(7-13)5-11(4-9)8-13/h9-11H,3-8,14H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a |
National and Kapodistrian University of Athens
Curated by ChEMBL
| Assay Description Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titration |
ACS Med Chem Lett 9: 198-203 (2018)
Article DOI: 10.1021/acsmedchemlett.7b00458 BindingDB Entry DOI: 10.7270/Q2GQ71F3 |
More data for this Ligand-Target Pair | |
Matrix protein 2
(Influenza A virus (A/Udorn/307/1972(H3N2))) | BDBM50465108
(CHEMBL4277543)Show SMILES CC(C)(N)C12CC3CC(CC(C3)C1)C2 |TLB:7:8:12:5.6.11,THB:7:6:12:13.8.9,9:8:5:12.10.11,9:10:5:13.8.7| Show InChI InChI=1S/C13H23N/c1-12(2,14)13-6-9-3-10(7-13)5-11(4-9)8-13/h9-11H,3-8,14H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a |
National and Kapodistrian University of Athens
Curated by ChEMBL
| Assay Description Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage c... |
ACS Med Chem Lett 9: 198-203 (2018)
Article DOI: 10.1021/acsmedchemlett.7b00458 BindingDB Entry DOI: 10.7270/Q2GQ71F3 |
More data for this Ligand-Target Pair | |
Matrix protein 2
(Influenza A virus (A/Udorn/307/1972(H3N2))) | BDBM50465108
(CHEMBL4277543)Show SMILES CC(C)(N)C12CC3CC(CC(C3)C1)C2 |TLB:7:8:12:5.6.11,THB:7:6:12:13.8.9,9:8:5:12.10.11,9:10:5:13.8.7| Show InChI InChI=1S/C13H23N/c1-12(2,14)13-6-9-3-10(7-13)5-11(4-9)8-13/h9-11H,3-8,14H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | 4.44E+5 | n/a | n/a | n/a | n/a | n/a |
National and Kapodistrian University of Athens
Curated by ChEMBL
| Assay Description Binding affinity to Influenza A virus A/Udorn/72 M2 proton channel S31N mutant expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage... |
ACS Med Chem Lett 9: 198-203 (2018)
Article DOI: 10.1021/acsmedchemlett.7b00458 BindingDB Entry DOI: 10.7270/Q2GQ71F3 |
More data for this Ligand-Target Pair | |