Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 459.4 BDBM50364390

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50364390 (CHEMBL1950312) Show SMILES CC(C)(NC(=O)CCN1CCC(CC1)c1ccccc1)c1nc2cc(Cl)c(Cl)cc2[nH]1 Show InChI InChI=1S/C24H28Cl2N4O/c1-24(2,23-27-20-14-18(25)19(26)15-21(20)28-23)29-22(31)10-13-30-11-8-17(9-12-30)16-6-4-3-5-7-16/h3-7,14-15,17H,8-13H2,1-2H3,(H,27,28)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	181	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate for 30 mins by continuous fluorimetric assay				Bioorg Med Chem Lett 22: 1774-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.064 BindingDB Entry DOI: 10.7270/Q27H1K28
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