Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Lysosomal Pro-X carboxypeptidase
(Homo sapiens (Human)) | BDBM50365009
(CHEMBL1950908)Show SMILES CC(C)(O)C1CCCN(C1)c1cc(ncn1)N1CCC[C@H]1c1nc2cc(Cl)c(Cl)cc2[nH]1 |r| Show InChI InChI=1S/C23H28Cl2N6O/c1-23(2,32)14-5-3-7-30(12-14)20-11-21(27-13-26-20)31-8-4-6-19(31)22-28-17-9-15(24)16(25)10-18(17)29-22/h9-11,13-14,19,32H,3-8,12H2,1-2H3,(H,28,29)/t14?,19-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate after 30 mins by fluorescence analysis |
Bioorg Med Chem Lett 22: 1727-30 (2012)
Article DOI: 10.1016/j.bmcl.2011.12.098
BindingDB Entry DOI: 10.7270/Q2GT5NNH |
More data for this
Ligand-Target Pair | |
Lysosomal Pro-X carboxypeptidase
(Mus musculus) | BDBM50365009
(CHEMBL1950908)Show SMILES CC(C)(O)C1CCCN(C1)c1cc(ncn1)N1CCC[C@H]1c1nc2cc(Cl)c(Cl)cc2[nH]1 |r| Show InChI InChI=1S/C23H28Cl2N6O/c1-23(2,32)14-5-3-7-30(12-14)20-11-21(27-13-26-20)31-8-4-6-19(31)22-28-17-9-15(24)16(25)10-18(17)29-22/h9-11,13-14,19,32H,3-8,12H2,1-2H3,(H,28,29)/t14?,19-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse recombinant PrCP assessed as angiotensin 3 cleavage after 8 mins by LC/MS analysis |
Bioorg Med Chem Lett 22: 1727-30 (2012)
Article DOI: 10.1016/j.bmcl.2011.12.098
BindingDB Entry DOI: 10.7270/Q2GT5NNH |
More data for this
Ligand-Target Pair | |