Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50069368
((R)-6-(3-(1-((1-(carboxymethyl)cyclopropyl)methylt...)Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc(cn2)C(O)=O)c1 Show InChI InChI=1S/C32H35NO5S/c1-31(2,38)27-9-4-3-7-23(27)12-15-28(39-21-32(16-17-32)19-29(34)35)24-8-5-6-22(18-24)10-13-26-14-11-25(20-33-26)30(36)37/h3-11,13-14,18,20,28,38H,12,15-17,19,21H2,1-2H3,(H,34,35)(H,36,37)/b13-10+/t28-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 421 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang University
Curated by ChEMBL
| Assay Description
Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L... |
Bioorg Med Chem 18: 5519-27 (2010)
Article DOI: 10.1016/j.bmc.2010.06.047
BindingDB Entry DOI: 10.7270/Q26D5TZ0 |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1/2
(Homo sapiens (Human)) | BDBM50069368
((R)-6-(3-(1-((1-(carboxymethyl)cyclopropyl)methylt...)Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc(cn2)C(O)=O)c1 Show InChI InChI=1S/C32H35NO5S/c1-31(2,38)27-9-4-3-7-23(27)12-15-28(39-21-32(16-17-32)19-29(34)35)24-8-5-6-22(18-24)10-13-26-14-11-25(20-33-26)30(36)37/h3-11,13-14,18,20,28,38H,12,15-17,19,21H2,1-2H3,(H,34,35)(H,36,37)/b13-10+/t28-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 421 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Center for Therapeutic Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA). |
Bioorg Med Chem Lett 8: 453-8 (1999)
BindingDB Entry DOI: 10.7270/Q2M907SH |
More data for this
Ligand-Target Pair | |