Found 4 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cysteinyl leukotriene receptor 1/2
(Homo sapiens (Human)) | BDBM50069372
((1-{(R)-1-{3-[(E)-2-(6,6-Dimethyl-6,7-dihydro-5H-[...)Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CC(C)(C)Cc3n2)c1 Show InChI InChI=1S/C36H43NO3S/c1-34(2)21-28-13-16-29(37-31(28)22-34)15-12-25-8-7-10-27(20-25)32(41-24-36(18-19-36)23-33(38)39)17-14-26-9-5-6-11-30(26)35(3,4)40/h5-13,15-16,20,32,40H,14,17-19,21-24H2,1-4H3,(H,38,39)/b15-12+/t32-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.340 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Center for Therapeutic Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA). |
Bioorg Med Chem Lett 8: 453-8 (1999)
BindingDB Entry DOI: 10.7270/Q2M907SH |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50069372
((1-{(R)-1-{3-[(E)-2-(6,6-Dimethyl-6,7-dihydro-5H-[...)Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CC(C)(C)Cc3n2)c1 Show InChI InChI=1S/C36H43NO3S/c1-34(2)21-28-13-16-29(37-31(28)22-34)15-12-25-8-7-10-27(20-25)32(41-24-36(18-19-36)23-33(38)39)17-14-26-9-5-6-11-30(26)35(3,4)40/h5-13,15-16,20,32,40H,14,17-19,21-24H2,1-4H3,(H,38,39)/b15-12+/t32-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.340 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang University
Curated by ChEMBL
| Assay Description
Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L... |
Bioorg Med Chem 18: 5519-27 (2010)
Article DOI: 10.1016/j.bmc.2010.06.047
BindingDB Entry DOI: 10.7270/Q26D5TZ0 |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1/2
(Homo sapiens (Human)) | BDBM50069372
((1-{(R)-1-{3-[(E)-2-(6,6-Dimethyl-6,7-dihydro-5H-[...)Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CC(C)(C)Cc3n2)c1 Show InChI InChI=1S/C36H43NO3S/c1-34(2)21-28-13-16-29(37-31(28)22-34)15-12-25-8-7-10-27(20-25)32(41-24-36(18-19-36)23-33(38)39)17-14-26-9-5-6-11-30(26)35(3,4)40/h5-13,15-16,20,32,40H,14,17-19,21-24H2,1-4H3,(H,38,39)/b15-12+/t32-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.430 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Center for Therapeutic Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA). |
Bioorg Med Chem Lett 8: 453-8 (1999)
BindingDB Entry DOI: 10.7270/Q2M907SH |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50069372
((1-{(R)-1-{3-[(E)-2-(6,6-Dimethyl-6,7-dihydro-5H-[...)Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CC(C)(C)Cc3n2)c1 Show InChI InChI=1S/C36H43NO3S/c1-34(2)21-28-13-16-29(37-31(28)22-34)15-12-25-8-7-10-27(20-25)32(41-24-36(18-19-36)23-33(38)39)17-14-26-9-5-6-11-30(26)35(3,4)40/h5-13,15-16,20,32,40H,14,17-19,21-24H2,1-4H3,(H,38,39)/b15-12+/t32-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.560 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Center for Therapeutic Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of DMSO differentiated human U937 cell membranes |
Bioorg Med Chem Lett 8: 453-8 (1999)
BindingDB Entry DOI: 10.7270/Q2M907SH |
More data for this
Ligand-Target Pair | |