Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 379.4 BDBM50511206

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50511206 (CHEMBL4467075) Show SMILES CC(C)(Oc1ccc(CNc2cccc(c2)C(O)=O)cc1)c1ccc(F)cc1 Show InChI InChI=1S/C23H22FNO3/c1-23(2,18-8-10-19(24)11-9-18)28-21-12-6-16(7-13-21)15-25-20-5-3-4-17(14-20)22(26)27/h3-14,25H,15H2,1-2H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8.52E+3	n/a	n/a	n/a	n/a
University of Oklahoma Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha expressed in nonhuman mammalian cells assessed as increase in receptor transcriptional activity incubated for 22 ...				J Med Chem 63: 2854-2876 (2020) Article DOI: 10.1021/acs.jmedchem.9b01189 BindingDB Entry DOI: 10.7270/Q2H998HT
					More data for this Ligand-Target Pair