Found 11 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Dual specificity protein kinase CLK4
(Mus musculus) | BDBM50259553
(CHEMBL4074132)Show SMILES CC(C)[C@@H](CO)Nc1ccc2ncc(-c3cccnc3)n2n1 |r| Show InChI InChI=1S/C16H19N5O/c1-11(2)13(10-22)19-15-5-6-16-18-9-14(21(16)20-15)12-4-3-7-17-8-12/h3-9,11,13,22H,10H2,1-2H3,(H,19,20)/t13-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
ManRos Therapeutics, Perharidy Research Center, 29680 Roscoff, Bretagne, France; Unité de Technologies Chimiques et Biologiques pour la Santé, Université Paris Descartes, UMR-S 1022 Inserm, 4 avenue
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant mouse CLK4 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
Article DOI: 10.1016/j.ejmech.2016.09.064
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50259553
(CHEMBL4074132)Show SMILES CC(C)[C@@H](CO)Nc1ccc2ncc(-c3cccnc3)n2n1 |r| Show InChI InChI=1S/C16H19N5O/c1-11(2)13(10-22)19-15-5-6-16-18-9-14(21(16)20-15)12-4-3-7-17-8-12/h3-9,11,13,22H,10H2,1-2H3,(H,19,20)/t13-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
ManRos Therapeutics, Perharidy Research Center, 29680 Roscoff, Bretagne, France; Unité de Technologies Chimiques et Biologiques pour la Santé, Université Paris Descartes, UMR-S 1022 Inserm, 4 avenue
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant human DYRK1B expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
Article DOI: 10.1016/j.ejmech.2016.09.064
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50259553
(CHEMBL4074132)Show SMILES CC(C)[C@@H](CO)Nc1ccc2ncc(-c3cccnc3)n2n1 |r| Show InChI InChI=1S/C16H19N5O/c1-11(2)13(10-22)19-15-5-6-16-18-9-14(21(16)20-15)12-4-3-7-17-8-12/h3-9,11,13,22H,10H2,1-2H3,(H,19,20)/t13-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
ManRos Therapeutics, Perharidy Research Center, 29680 Roscoff, Bretagne, France; Unité de Technologies Chimiques et Biologiques pour la Santé, Université Paris Descartes, UMR-S 1022 Inserm, 4 avenue
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant mouse CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
Article DOI: 10.1016/j.ejmech.2016.09.064
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human)) | BDBM50259553
(CHEMBL4074132)Show SMILES CC(C)[C@@H](CO)Nc1ccc2ncc(-c3cccnc3)n2n1 |r| Show InChI InChI=1S/C16H19N5O/c1-11(2)13(10-22)19-15-5-6-16-18-9-14(21(16)20-15)12-4-3-7-17-8-12/h3-9,11,13,22H,10H2,1-2H3,(H,19,20)/t13-/m1/s1 | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
ManRos Therapeutics, Perharidy Research Center, 29680 Roscoff, Bretagne, France; Unité de Technologies Chimiques et Biologiques pour la Santé, Université Paris Descartes, UMR-S 1022 Inserm, 4 avenue
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant human DYRK2 expressed in Escherichia coli using using woodtide as substrate after 30 mins by [gamma-33P]ATP base... |
Eur J Med Chem 125: 696-709 (2017)
Article DOI: 10.1016/j.ejmech.2016.09.064
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 3
(Homo sapiens (Human)) | BDBM50259553
(CHEMBL4074132)Show SMILES CC(C)[C@@H](CO)Nc1ccc2ncc(-c3cccnc3)n2n1 |r| Show InChI InChI=1S/C16H19N5O/c1-11(2)13(10-22)19-15-5-6-16-18-9-14(21(16)20-15)12-4-3-7-17-8-12/h3-9,11,13,22H,10H2,1-2H3,(H,19,20)/t13-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
ManRos Therapeutics, Perharidy Research Center, 29680 Roscoff, Bretagne, France; Unité de Technologies Chimiques et Biologiques pour la Santé, Université Paris Descartes, UMR-S 1022 Inserm, 4 avenue
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant human DYRK3 expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based scin... |
Eur J Med Chem 125: 696-709 (2017)
Article DOI: 10.1016/j.ejmech.2016.09.064
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50259553
(CHEMBL4074132)Show SMILES CC(C)[C@@H](CO)Nc1ccc2ncc(-c3cccnc3)n2n1 |r| Show InChI InChI=1S/C16H19N5O/c1-11(2)13(10-22)19-15-5-6-16-18-9-14(21(16)20-15)12-4-3-7-17-8-12/h3-9,11,13,22H,10H2,1-2H3,(H,19,20)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
ManRos Therapeutics, Perharidy Research Center, 29680 Roscoff, Bretagne, France; Unité de Technologies Chimiques et Biologiques pour la Santé, Université Paris Descartes, UMR-S 1022 Inserm, 4 avenue
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant human DYRK1A expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
Article DOI: 10.1016/j.ejmech.2016.09.064
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Mus musculus) | BDBM50259553
(CHEMBL4074132)Show SMILES CC(C)[C@@H](CO)Nc1ccc2ncc(-c3cccnc3)n2n1 |r| Show InChI InChI=1S/C16H19N5O/c1-11(2)13(10-22)19-15-5-6-16-18-9-14(21(16)20-15)12-4-3-7-17-8-12/h3-9,11,13,22H,10H2,1-2H3,(H,19,20)/t13-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
ManRos Therapeutics, Perharidy Research Center, 29680 Roscoff, Bretagne, France; Unité de Technologies Chimiques et Biologiques pour la Santé, Université Paris Descartes, UMR-S 1022 Inserm, 4 avenue
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant mouse CLK2 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
Article DOI: 10.1016/j.ejmech.2016.09.064
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM50259553
(CHEMBL4074132)Show SMILES CC(C)[C@@H](CO)Nc1ccc2ncc(-c3cccnc3)n2n1 |r| Show InChI InChI=1S/C16H19N5O/c1-11(2)13(10-22)19-15-5-6-16-18-9-14(21(16)20-15)12-4-3-7-17-8-12/h3-9,11,13,22H,10H2,1-2H3,(H,19,20)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ManRos Therapeutics, Perharidy Research Center, 29680 Roscoff, Bretagne, France; Unité de Technologies Chimiques et Biologiques pour la Santé, Université Paris Descartes, UMR-S 1022 Inserm, 4 avenue
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CDK9/cyclin T expressed in insect cells using CDK7/9-tide as substrate after 30 mins by [gamma-33P]ATP based scintill... |
Eur J Med Chem 125: 696-709 (2017)
Article DOI: 10.1016/j.ejmech.2016.09.064
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50259553
(CHEMBL4074132)Show SMILES CC(C)[C@@H](CO)Nc1ccc2ncc(-c3cccnc3)n2n1 |r| Show InChI InChI=1S/C16H19N5O/c1-11(2)13(10-22)19-15-5-6-16-18-9-14(21(16)20-15)12-4-3-7-17-8-12/h3-9,11,13,22H,10H2,1-2H3,(H,19,20)/t13-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ManRos Therapeutics, Perharidy Research Center, 29680 Roscoff, Bretagne, France; Unité de Technologies Chimiques et Biologiques pour la Santé, Université Paris Descartes, UMR-S 1022 Inserm, 4 avenue
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by [gamma-33P]ATP based scintillation counting analysis |
Eur J Med Chem 125: 696-709 (2017)
Article DOI: 10.1016/j.ejmech.2016.09.064
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50259553
(CHEMBL4074132)Show SMILES CC(C)[C@@H](CO)Nc1ccc2ncc(-c3cccnc3)n2n1 |r| Show InChI InChI=1S/C16H19N5O/c1-11(2)13(10-22)19-15-5-6-16-18-9-14(21(16)20-15)12-4-3-7-17-8-12/h3-9,11,13,22H,10H2,1-2H3,(H,19,20)/t13-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ManRos Therapeutics, Perharidy Research Center, 29680 Roscoff, Bretagne, France; Unité de Technologies Chimiques et Biologiques pour la Santé, Université Paris Descartes, UMR-S 1022 Inserm, 4 avenue
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CDK2/cyclin A after 30 mins by [gamma-33P]ATP based scintillation counting analysis |
Eur J Med Chem 125: 696-709 (2017)
Article DOI: 10.1016/j.ejmech.2016.09.064
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK3
(Mus musculus) | BDBM50259553
(CHEMBL4074132)Show SMILES CC(C)[C@@H](CO)Nc1ccc2ncc(-c3cccnc3)n2n1 |r| Show InChI InChI=1S/C16H19N5O/c1-11(2)13(10-22)19-15-5-6-16-18-9-14(21(16)20-15)12-4-3-7-17-8-12/h3-9,11,13,22H,10H2,1-2H3,(H,19,20)/t13-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ManRos Therapeutics, Perharidy Research Center, 29680 Roscoff, Bretagne, France; Unité de Technologies Chimiques et Biologiques pour la Santé, Université Paris Descartes, UMR-S 1022 Inserm, 4 avenue
Curated by ChEMBL
| Assay Description
Inhibition of GST tagged recombinant mouse CLK3 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci... |
Eur J Med Chem 125: 696-709 (2017)
Article DOI: 10.1016/j.ejmech.2016.09.064
BindingDB Entry DOI: 10.7270/Q2M61NPG |
More data for this
Ligand-Target Pair | |