Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 384.3 BDBM589992

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM589992 ((S)-1-(4-(6-amino-5-(trifluoromethyl)pyridin-3-yl)...) Show SMILES CC(C)[C@H](O)c1nc(cn1C12CC(F)(C1)C2)-c1cnc(N)c(c1)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...				Citation and Details BindingDB Entry DOI: 10.7270/Q21C21S6
					More data for this Ligand-Target Pair