Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM451506
(US10710967, Example 103 | US10710967, Example 217)Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(cc(=O)[nH]1)-c1cnc(nc1)C(F)(F)F Show InChI InChI=1S/C20H17ClF3N5O2/c1-10(2)18(31)25-7-11-3-4-14(21)13(5-11)17-28-15(6-16(30)29-17)12-8-26-19(27-9-12)20(22,23)24/h3-6,8-10H,7H2,1-2H3,(H,25,31)(H,28,29,30) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
ASKA PHARMACEUTICAL CO., LTD.
US Patent
| Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES... |
US Patent US10710967 (2020)
BindingDB Entry DOI: 10.7270/Q2NZ8BP9 |
More data for this Ligand-Target Pair | |
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM451506
(US10710967, Example 103 | US10710967, Example 217)Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(cc(=O)[nH]1)-c1cnc(nc1)C(F)(F)F Show InChI InChI=1S/C20H17ClF3N5O2/c1-10(2)18(31)25-7-11-3-4-14(21)13(5-11)17-28-15(6-16(30)29-17)12-8-26-19(27-9-12)20(22,23)24/h3-6,8-10H,7H2,1-2H3,(H,25,31)(H,28,29,30) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
ASKA PHARMACEUTICAL CO., LTD.
US Patent
| Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES... |
US Patent US10710967 (2020)
BindingDB Entry DOI: 10.7270/Q2NZ8BP9 |
More data for this Ligand-Target Pair | |