Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Angiotensin-converting enzyme
(Homo sapiens (Human)) | BDBM50266277
((2R)-3-(1-(4-isopropylphenyl)-2-methylpropylthio)-...)Show SMILES CC(C)C(SC[C@H](NC(=O)[C@H](C)CS)C(O)=O)c1ccc(cc1)C(C)C |r| Show InChI InChI=1S/C20H31NO3S2/c1-12(2)15-6-8-16(9-7-15)18(13(3)4)26-11-17(20(23)24)21-19(22)14(5)10-25/h6-9,12-14,17-18,25H,10-11H2,1-5H3,(H,21,22)(H,23,24)/t14-,17+,18?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
Santen Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of angiotensin-converting enzyme (unknown origin) in whole blood by HPLC |
Bioorg Med Chem Lett 19: 442-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.042
BindingDB Entry DOI: 10.7270/Q20K28FC |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Cavia porcellus) | BDBM50266277
((2R)-3-(1-(4-isopropylphenyl)-2-methylpropylthio)-...)Show SMILES CC(C)C(SC[C@H](NC(=O)[C@H](C)CS)C(O)=O)c1ccc(cc1)C(C)C |r| Show InChI InChI=1S/C20H31NO3S2/c1-12(2)15-6-8-16(9-7-15)18(13(3)4)26-11-17(20(23)24)21-19(22)14(5)10-25/h6-9,12-14,17-18,25H,10-11H2,1-5H3,(H,21,22)(H,23,24)/t14-,17+,18?/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
Santen Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 production |
Bioorg Med Chem Lett 19: 442-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.042
BindingDB Entry DOI: 10.7270/Q20K28FC |
More data for this
Ligand-Target Pair | |