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Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 308.3
BDBM50046325

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cytosol aminopeptidase (Homo sapiens (Human))	BDBM50046325 ((S)-2-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyryla...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of Leucine aminopeptidase and the inhibition constant was determined after preincubating the enzyme and inh...				J Med Chem 27: 417-22 (1984) BindingDB Entry DOI: 10.7270/Q280535G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50046325 ((S)-2-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyryla...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Effect of inhibitor structure on the slow binding inhibition of aminopeptidase M was determined and Ki* was reported which is obtained by the equatio...				J Med Chem 27: 417-22 (1984) BindingDB Entry DOI: 10.7270/Q280535G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Aminopeptidase N (Sus scrofa (Pig))	BDBM50046325 ((S)-2-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyryla...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Effect of inhibitor structure on the slow binding inhibition of aminopeptidase M was determined and the Ki was reported which is = k2/k1				J Med Chem 27: 417-22 (1984) BindingDB Entry DOI: 10.7270/Q280535G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Aminopeptidase B (Rattus norvegicus)	BDBM50046325 ((S)-2-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyryla...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat liver aminopeptidase B using 0.2 mM L-leucine-beta-naphthylamide by colorimetry				J Med Chem 20: 510-5 (1977) BindingDB Entry DOI: 10.7270/Q29W0H11
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50046325 ((S)-2-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyryla...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytes				J Med Chem 36: 211-20 (1993) BindingDB Entry DOI: 10.7270/Q2T152P3
Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)