Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 967.1 BDBM50542834

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 21 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]UR-KK200 from human neuropeptide Y Y4 receptor expressed in CHO-mtAEQ cells co-expressing Gqi5 measured after 90 mins by scintill...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01574 BindingDB Entry DOI: 10.7270/Q2VH5SNG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of [3H]UR-KK200 from human Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ measured after 90 mins by scintillation counting ...				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of [3H]UR-KK200 from human Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ measured after 90 mins by scintillation counting ...				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]UR-MK299 from human neuropeptide Y Y2 receptor expressed in CHO cells measured after 90 mins by scintillation counting analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01574 BindingDB Entry DOI: 10.7270/Q2VH5SNG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]UR-MK299 from human neuropeptide Y Y1 receptor in human SK-N-MC cells measured after 90 mins by scintillation counting analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01574 BindingDB Entry DOI: 10.7270/Q2VH5SNG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of [3H]UR-MK299 from Y1 receptor in human SK-N-MC cells				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of [3H]propionyl-pNPY from human Y5 receptor expressed in human HEC1B cells				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]propionyl-pNPY from human neuropeptide Y Y5 receptor in human HEC-1B cells measured after 90 mins by scintillation counting analy...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01574 BindingDB Entry DOI: 10.7270/Q2VH5SNG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of [3H]propionyl-pNPY from human Y2 receptor expressed in CHO cells measured after 2 hrs by microbeta liquid scintillation counting anal...				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	<3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of [3H]UR-MK299 from Y1 receptor in human SK-N-MC cells				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	<3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of [3H]propionyl-pNPY from human Y5 receptor expressed in human HEC1B cells				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	<3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of [3H]propionyl-pNPY from human Y2 receptor expressed in CHO cells measured after 2 hrs by microbeta liquid scintillation counting anal...				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human neuropeptide Y Y4 receptor expressed in HEK293T-ARRB2 cells assessed as stimulation of beta-arrestin 2 recruitment by multi...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01574 BindingDB Entry DOI: 10.7270/Q2VH5SNG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human neuropeptide Y Y4 receptor expressed in HEK293T-ARRB1 cells assessed as stimulation of beta-arrestin 1 recruitment by multi...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01574 BindingDB Entry DOI: 10.7270/Q2VH5SNG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at human Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ assessed as intracellular calcium mobilization measured for 43 ...				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	182	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at human Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ assessed as intracellular calcium mobilization measured for 43 ...				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB2 assessed as induction of beta-arrestin2 recruitment measured for 40 mins...				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human neuropeptide Y Y4 receptor expressed in CHO-mtAEQ cells co-expressing Gqi5 by calcium aequorin assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01574 BindingDB Entry DOI: 10.7270/Q2VH5SNG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB1 assessed as induction of beta-arrestin1 recruitment measured for 40 mins...				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	162	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB1 assessed as induction of beta-arrestin1 recruitment measured for 40 mins...				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50542834 (CHEMBL4633593) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C44H70N16O9/c1-24(2)21-34(40(68)56-31(8-5-19-53-43(48)49)38(66)58-33(36(45)64)22-26-10-14-28(62)15-11-26)59-39(67)32(9-6-20-54-44(50)51)57-41(69)35(23-27-12-16-29(63)17-13-27)60-37(65)30(55-25(3)61)7-4-18-52-42(46)47/h10-17,24,30-35,62-63H,4-9,18-23H2,1-3H3,(H2,45,64)(H,55,61)(H,56,68)(H,57,69)(H,58,66)(H,59,67)(H,60,65)(H4,46,47,52)(H4,48,49,53)(H4,50,51,54)/t30-,31-,32-,33-,34-,35-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	112	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB2 assessed as induction of beta-arrestin2 recruitment measured for 40 mins...				J Med Chem 63: 8198-8215 (2020) Article DOI: 10.1021/acs.jmedchem.0c00426 BindingDB Entry DOI: 10.7270/Q22R3W7V
					More data for this Ligand-Target Pair