Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 2
(RAT) | BDBM50091687
(CHEMBL263350 | N-alpha-Ac-[Tic27]PYY(22-36)-NH2(N-...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1Cc2ccccc2CC1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O Show InChI InChI=1S/C87H139N29O21/c1-42(2)31-59(109-80(133)64(40-117)113-71(124)46(9)102-48(11)119)76(129)104-55(20-15-29-99-86(93)94)74(127)112-63(36-52-38-97-41-101-52)84(137)116-39-51-18-13-12-17-50(51)35-65(116)81(134)111-60(32-43(3)4)77(130)110-62(37-67(89)122)78(131)108-61(33-44(5)6)79(132)114-68(45(7)8)82(135)115-69(47(10)118)83(136)106-56(21-16-30-100-87(95)96)72(125)105-57(26-27-66(88)121)75(128)103-54(19-14-28-98-85(91)92)73(126)107-58(70(90)123)34-49-22-24-53(120)25-23-49/h12-13,17-18,22-25,38,41-47,54-65,68-69,117-118,120H,14-16,19-21,26-37,39-40H2,1-11H3,(H2,88,121)(H2,89,122)(H2,90,123)(H,97,101)(H,102,119)(H,103,128)(H,104,129)(H,105,125)(H,106,136)(H,107,126)(H,108,131)(H,109,133)(H,110,130)(H,111,134)(H,112,127)(H,113,124)(H,114,132)(H,115,135)(H4,91,92,98)(H4,93,94,99)(H4,95,96,100)/t46-,47+,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65?,68-,69-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet 
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cincinnati Medical Center
Curated by ChEMBL
| Assay Description
Antisecretory potency, affinity for intestinal PYY of rat jejunum by using short circuit current (SCC) method. |
J Med Chem 43: 3420-7 (2000)
BindingDB Entry DOI: 10.7270/Q2QR4WCX |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50091687
(CHEMBL263350 | N-alpha-Ac-[Tic27]PYY(22-36)-NH2(N-...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1Cc2ccccc2CC1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O Show InChI InChI=1S/C87H139N29O21/c1-42(2)31-59(109-80(133)64(40-117)113-71(124)46(9)102-48(11)119)76(129)104-55(20-15-29-99-86(93)94)74(127)112-63(36-52-38-97-41-101-52)84(137)116-39-51-18-13-12-17-50(51)35-65(116)81(134)111-60(32-43(3)4)77(130)110-62(37-67(89)122)78(131)108-61(33-44(5)6)79(132)114-68(45(7)8)82(135)115-69(47(10)118)83(136)106-56(21-16-30-100-87(95)96)72(125)105-57(26-27-66(88)121)75(128)103-54(19-14-28-98-85(91)92)73(126)107-58(70(90)123)34-49-22-24-53(120)25-23-49/h12-13,17-18,22-25,38,41-47,54-65,68-69,117-118,120H,14-16,19-21,26-37,39-40H2,1-11H3,(H2,88,121)(H2,89,122)(H2,90,123)(H,97,101)(H,102,119)(H,103,128)(H,104,129)(H,105,125)(H,106,136)(H,107,126)(H,108,131)(H,109,133)(H,110,130)(H,111,134)(H,112,127)(H,113,124)(H,114,132)(H,115,135)(H4,91,92,98)(H4,93,94,99)(H4,95,96,100)/t46-,47+,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65?,68-,69-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 186 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cincinnati Medical Center
Curated by ChEMBL
| Assay Description
Affinity against Neuropeptide Y receptor Y2 in SK-N-BE2 cell line |
J Med Chem 43: 3420-7 (2000)
BindingDB Entry DOI: 10.7270/Q2QR4WCX |
More data for this
Ligand-Target Pair | |