Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50361353
(CHEMBL1933825)Show SMILES CC(C)CCS(=O)(=O)NC(=O)CCc1cc(OC(C)C)nn1Cc1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H29Cl2N3O4S/c1-14(2)9-10-31(28,29)25-20(27)8-7-18-12-21(30-15(3)4)24-26(18)13-16-5-6-17(22)11-19(16)23/h5-6,11-12,14-15H,7-10,13H2,1-4H3,(H,25,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description Agonist activity at human PPARdelta expressed in COS-1 cells after 2 days by luciferase reporter gene transactivation assay |
Bioorg Med Chem 20: 714-33 (2012)
Article DOI: 10.1016/j.bmc.2011.12.008 BindingDB Entry DOI: 10.7270/Q2PK0GK3 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50361353
(CHEMBL1933825)Show SMILES CC(C)CCS(=O)(=O)NC(=O)CCc1cc(OC(C)C)nn1Cc1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H29Cl2N3O4S/c1-14(2)9-10-31(28,29)25-20(27)8-7-18-12-21(30-15(3)4)24-26(18)13-16-5-6-17(22)11-19(16)23/h5-6,11-12,14-15H,7-10,13H2,1-4H3,(H,25,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description Agonist activity at full length human PPARgamma1 transfected in human CHOK1 cells co expressing RXRalpha and PPRE after 1 day by luciferase reporter ... |
Bioorg Med Chem 20: 714-33 (2012)
Article DOI: 10.1016/j.bmc.2011.12.008 BindingDB Entry DOI: 10.7270/Q2PK0GK3 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50361353
(CHEMBL1933825)Show SMILES CC(C)CCS(=O)(=O)NC(=O)CCc1cc(OC(C)C)nn1Cc1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H29Cl2N3O4S/c1-14(2)9-10-31(28,29)25-20(27)8-7-18-12-21(30-15(3)4)24-26(18)13-16-5-6-17(22)11-19(16)23/h5-6,11-12,14-15H,7-10,13H2,1-4H3,(H,25,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha expressed in COS-1 cells after 1 day by luciferase reporter gene transactivation assay |
Bioorg Med Chem 20: 714-33 (2012)
Article DOI: 10.1016/j.bmc.2011.12.008 BindingDB Entry DOI: 10.7270/Q2PK0GK3 |
More data for this Ligand-Target Pair | |