Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 487.5 BDBM367499

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human))	BDBM367499 ((6RS)-2-[2-(Acetylamino)pyridin-4-yl]-N,6-dimethyl...) Show SMILES CC(C)CN(C)C(=O)C1(C)Cc2[nH]c(c(Nc3ccccc3)c2C(=O)C1)-c1ccnc(NC(C)=O)c1 |w:8.7,8.8| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...				J Med Chem 51: 1377-84 (2008) BindingDB Entry DOI: 10.7270/Q2QN6931
					More data for this Ligand-Target Pair