Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50256203
((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)Show SMILES CC(C)NC(=O)c1noc(n1)[C@H](CCCC1CCCCC1)CC(=O)NO |r| Show InChI InChI=1S/C18H30N4O4/c1-12(2)19-17(24)16-20-18(26-22-16)14(11-15(23)21-25)10-6-9-13-7-4-3-5-8-13/h12-14,25H,3-11H2,1-2H3,(H,19,24)(H,21,23)/t14-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation counting |
Bioorg Med Chem Lett 18: 6562-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.036
BindingDB Entry DOI: 10.7270/Q2J1031M |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50256203
((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)Show SMILES CC(C)NC(=O)c1noc(n1)[C@H](CCCC1CCCCC1)CC(=O)NO |r| Show InChI InChI=1S/C18H30N4O4/c1-12(2)19-17(24)16-20-18(26-22-16)14(11-15(23)21-25)10-6-9-13-7-4-3-5-8-13/h12-14,25H,3-11H2,1-2H3,(H,19,24)(H,21,23)/t14-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human MMP2 by fluorescence assay |
Bioorg Med Chem Lett 18: 6562-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.036
BindingDB Entry DOI: 10.7270/Q2J1031M |
More data for this
Ligand-Target Pair | |