Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 310.3 BDBM50508615

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508615 (CHEMBL4549181) Show SMILES CC(C)Nc1sc(C(=O)c2ccc(cc2)C#N)c(N)c1C#N Show InChI InChI=1S/C16H14N4OS/c1-9(2)20-16-12(8-18)13(19)15(22-16)14(21)11-5-3-10(7-17)4-6-11/h3-6,9,20H,19H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair