Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 310.8 BDBM50508582

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508582 (CHEMBL4468259) Show SMILES CC(C)Nc1sc(cc1C#N)C(=O)c1ccc(Cl)s1 Show InChI InChI=1S/C13H11ClN2OS2/c1-7(2)16-13-8(6-15)5-10(19-13)12(17)9-3-4-11(14)18-9/h3-5,7,16H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair