Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Adenosylhomocysteinase
(Homo sapiens (Human)) | BDBM50515223
(CHEMBL4522602)Show SMILES CC(C)OC(=O)[C@H](C)N[P@](=O)(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](n2cnc3c(N)ncnc23)C1(F)F)Oc1ccccc1 |r| Show InChI InChI=1S/C23H29F2N6O7P/c1-12(2)37-22(34)13(3)30-39(35,38-14-7-5-4-6-8-14)36-9-15-17(32)18(33)19(23(15,24)25)31-11-29-16-20(26)27-10-28-21(16)31/h4-8,10-13,15,17-19,32-33H,9H2,1-3H3,(H,30,35)(H2,26,27,28)/t13-,15+,17+,18+,19-,39-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Inhibition of human placental SAH hydrolase expressed in Escherichia coli JM109 using SAH as substrate preincubated for 10 mins followed by SAH addit... |
J Med Chem 62: 6346-6362 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00781
BindingDB Entry DOI: 10.7270/Q25Q50GK |
More data for this
Ligand-Target Pair | |
Genome polyprotein
(Zika virus) | BDBM50515223
(CHEMBL4522602)Show SMILES CC(C)OC(=O)[C@H](C)N[P@](=O)(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](n2cnc3c(N)ncnc23)C1(F)F)Oc1ccccc1 |r| Show InChI InChI=1S/C23H29F2N6O7P/c1-12(2)37-22(34)13(3)30-39(35,38-14-7-5-4-6-8-14)36-9-15-17(32)18(33)19(23(15,24)25)31-11-29-16-20(26)27-10-28-21(16)31/h4-8,10-13,15,17-19,32-33H,9H2,1-3H3,(H,30,35)(H2,26,27,28)/t13-,15+,17+,18+,19-,39-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.75E+3 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath... |
J Med Chem 62: 6346-6362 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00781
BindingDB Entry DOI: 10.7270/Q25Q50GK |
More data for this
Ligand-Target Pair | |