Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Insulin receptor
(Homo sapiens (Human)) | BDBM50436864
(CHEMBL2403832)Show SMILES CC(C)Oc1cc(C2CCN(C)CC2)c(C)cc1Nc1cc(Nc2ccccc2S(=O)(=O)C(C)C)c(Cl)cn1 Show InChI InChI=1S/C30H39ClN4O3S/c1-19(2)38-28-16-23(22-11-13-35(6)14-12-22)21(5)15-27(28)34-30-17-26(24(31)18-32-30)33-25-9-7-8-10-29(25)39(36,37)20(3)4/h7-10,15-20,22H,11-14H2,1-6H3,(H2,32,33,34) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
| Assay Description
Inhibition of TEL-fused insulin receptor (unknown origin) expressed in mouse BAF3 cells after 2 to 3 days by luciferase reporter gene assay |
J Med Chem 56: 5675-90 (2014)
Article DOI: 10.1021/jm400402q
BindingDB Entry DOI: 10.7270/Q2G1627J |
More data for this
Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50436864
(CHEMBL2403832)Show SMILES CC(C)Oc1cc(C2CCN(C)CC2)c(C)cc1Nc1cc(Nc2ccccc2S(=O)(=O)C(C)C)c(Cl)cn1 Show InChI InChI=1S/C30H39ClN4O3S/c1-19(2)38-28-16-23(22-11-13-35(6)14-12-22)21(5)15-27(28)34-30-17-26(24(31)18-32-30)33-25-9-7-8-10-29(25)39(36,37)20(3)4/h7-10,15-20,22H,11-14H2,1-6H3,(H2,32,33,34) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
| Assay Description
Inhibition of NPM-fused ALK (unknown origin) expressed in mouse BAF3 cells after 2 to 3 days by luciferase reporter gene assay |
J Med Chem 56: 5675-90 (2014)
Article DOI: 10.1021/jm400402q
BindingDB Entry DOI: 10.7270/Q2G1627J |
More data for this
Ligand-Target Pair | |