Found 4 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50211315
(CHEMBL234854 | N-((1s,4s)-4-(4-(2-isopropoxyphenyl...)Show SMILES CC(C)Oc1ccccc1N1CCN(CC1)[C@@H]1CC[C@@H](CC1)NS(=O)(=O)c1cccnc1 |wU:16.17,19.24,(-6.93,-41.36,;-7.71,-42.69,;-9.25,-42.67,;-6.96,-44.03,;-7.75,-45.36,;-9.29,-45.34,;-10.07,-46.66,;-9.31,-48.01,;-7.77,-48.02,;-6.99,-46.7,;-5.46,-46.72,;-4.7,-48.06,;-3.16,-48.07,;-2.38,-46.75,;-3.13,-45.42,;-4.67,-45.4,;-.85,-46.77,;-.09,-48.12,;1.44,-48.14,;2.23,-46.82,;1.48,-45.47,;-.07,-45.45,;3.79,-46.85,;4.56,-45.52,;3.23,-44.75,;5.89,-46.29,;5.32,-44.18,;4.55,-42.86,;5.3,-41.53,;6.85,-41.51,;7.63,-42.84,;6.87,-44.17,)| Show InChI InChI=1S/C24H34N4O3S/c1-19(2)31-24-8-4-3-7-23(24)28-16-14-27(15-17-28)21-11-9-20(10-12-21)26-32(29,30)22-6-5-13-25-18-22/h3-8,13,18-21,26H,9-12,14-17H2,1-2H3/t20-,21+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development L.L.C.
Curated by ChEMBL
| Assay Description
Binding affinity to human cloned adrenergic alpha1A receptor |
Bioorg Med Chem Lett 17: 3292-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.008
BindingDB Entry DOI: 10.7270/Q2PG1RDH |
More data for this
Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50211315
(CHEMBL234854 | N-((1s,4s)-4-(4-(2-isopropoxyphenyl...)Show SMILES CC(C)Oc1ccccc1N1CCN(CC1)[C@@H]1CC[C@@H](CC1)NS(=O)(=O)c1cccnc1 |wU:16.17,19.24,(-6.93,-41.36,;-7.71,-42.69,;-9.25,-42.67,;-6.96,-44.03,;-7.75,-45.36,;-9.29,-45.34,;-10.07,-46.66,;-9.31,-48.01,;-7.77,-48.02,;-6.99,-46.7,;-5.46,-46.72,;-4.7,-48.06,;-3.16,-48.07,;-2.38,-46.75,;-3.13,-45.42,;-4.67,-45.4,;-.85,-46.77,;-.09,-48.12,;1.44,-48.14,;2.23,-46.82,;1.48,-45.47,;-.07,-45.45,;3.79,-46.85,;4.56,-45.52,;3.23,-44.75,;5.89,-46.29,;5.32,-44.18,;4.55,-42.86,;5.3,-41.53,;6.85,-41.51,;7.63,-42.84,;6.87,-44.17,)| Show InChI InChI=1S/C24H34N4O3S/c1-19(2)31-24-8-4-3-7-23(24)28-16-14-27(15-17-28)21-11-9-20(10-12-21)26-32(29,30)22-6-5-13-25-18-22/h3-8,13,18-21,26H,9-12,14-17H2,1-2H3/t20-,21+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development L.L.C.
Curated by ChEMBL
| Assay Description
Binding affinity to human dopamine D2 receptor |
Bioorg Med Chem Lett 17: 3292-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.008
BindingDB Entry DOI: 10.7270/Q2PG1RDH |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50211315
(CHEMBL234854 | N-((1s,4s)-4-(4-(2-isopropoxyphenyl...)Show SMILES CC(C)Oc1ccccc1N1CCN(CC1)[C@@H]1CC[C@@H](CC1)NS(=O)(=O)c1cccnc1 |wU:16.17,19.24,(-6.93,-41.36,;-7.71,-42.69,;-9.25,-42.67,;-6.96,-44.03,;-7.75,-45.36,;-9.29,-45.34,;-10.07,-46.66,;-9.31,-48.01,;-7.77,-48.02,;-6.99,-46.7,;-5.46,-46.72,;-4.7,-48.06,;-3.16,-48.07,;-2.38,-46.75,;-3.13,-45.42,;-4.67,-45.4,;-.85,-46.77,;-.09,-48.12,;1.44,-48.14,;2.23,-46.82,;1.48,-45.47,;-.07,-45.45,;3.79,-46.85,;4.56,-45.52,;3.23,-44.75,;5.89,-46.29,;5.32,-44.18,;4.55,-42.86,;5.3,-41.53,;6.85,-41.51,;7.63,-42.84,;6.87,-44.17,)| Show InChI InChI=1S/C24H34N4O3S/c1-19(2)31-24-8-4-3-7-23(24)28-16-14-27(15-17-28)21-11-9-20(10-12-21)26-32(29,30)22-6-5-13-25-18-22/h3-8,13,18-21,26H,9-12,14-17H2,1-2H3/t20-,21+ | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development L.L.C.
Curated by ChEMBL
| Assay Description
Binding affinity to human cloned adrenergic alpha1D receptor |
Bioorg Med Chem Lett 17: 3292-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.008
BindingDB Entry DOI: 10.7270/Q2PG1RDH |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50211315
(CHEMBL234854 | N-((1s,4s)-4-(4-(2-isopropoxyphenyl...)Show SMILES CC(C)Oc1ccccc1N1CCN(CC1)[C@@H]1CC[C@@H](CC1)NS(=O)(=O)c1cccnc1 |wU:16.17,19.24,(-6.93,-41.36,;-7.71,-42.69,;-9.25,-42.67,;-6.96,-44.03,;-7.75,-45.36,;-9.29,-45.34,;-10.07,-46.66,;-9.31,-48.01,;-7.77,-48.02,;-6.99,-46.7,;-5.46,-46.72,;-4.7,-48.06,;-3.16,-48.07,;-2.38,-46.75,;-3.13,-45.42,;-4.67,-45.4,;-.85,-46.77,;-.09,-48.12,;1.44,-48.14,;2.23,-46.82,;1.48,-45.47,;-.07,-45.45,;3.79,-46.85,;4.56,-45.52,;3.23,-44.75,;5.89,-46.29,;5.32,-44.18,;4.55,-42.86,;5.3,-41.53,;6.85,-41.51,;7.63,-42.84,;6.87,-44.17,)| Show InChI InChI=1S/C24H34N4O3S/c1-19(2)31-24-8-4-3-7-23(24)28-16-14-27(15-17-28)21-11-9-20(10-12-21)26-32(29,30)22-6-5-13-25-18-22/h3-8,13,18-21,26H,9-12,14-17H2,1-2H3/t20-,21+ | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development L.L.C.
Curated by ChEMBL
| Assay Description
Binding affinity to human cloned adrenergic alpha1B receptor |
Bioorg Med Chem Lett 17: 3292-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.008
BindingDB Entry DOI: 10.7270/Q2PG1RDH |
More data for this
Ligand-Target Pair | |