Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 382.3 BDBM365283

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM365283 (US9868720, No. 350 | [2-Isopropoxy-6-(tetrahydro- ...) Show SMILES CC(C)Oc1nc(Nc2cc(ccn2)C(F)(F)F)cc(n1)C1CCOCC1 Show InChI InChI=1S/C18H21F3N4O2/c1-11(2)27-17-23-14(12-4-7-26-8-5-12)10-16(25-17)24-15-9-13(3-6-22-15)18(19,20)21/h3,6,9-12H,4-5,7-8H2,1-2H3,(H,22,23,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	47.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2J38VWN
					More data for this Ligand-Target Pair