Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 298.4 BDBM50141708

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM50141708 ((R)-3-Amino-2-hydroxy-5-isopropylsulfanyl-pentanoi...) Show SMILES CC(C)SCC[C@@H](N)[C@H](O)C(=O)NOc1ccccc1 Show InChI InChI=1S/C14H22N2O3S/c1-10(2)20-9-8-12(15)13(17)14(18)16-19-11-6-4-3-5-7-11/h3-7,10,12-13,17H,8-9,15H2,1-2H3,(H,16,18)/t12-,13+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against human methionine aminopeptidase-2				Bioorg Med Chem Lett 14: 865-8 (2004) Article DOI: 10.1016/j.bmcl.2003.12.031 BindingDB Entry DOI: 10.7270/Q2Z31Z3N
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50141708 ((R)-3-Amino-2-hydroxy-5-isopropylsulfanyl-pentanoi...) Show SMILES CC(C)SCC[C@@H](N)[C@H](O)C(=O)NOc1ccccc1 Show InChI InChI=1S/C14H22N2O3S/c1-10(2)20-9-8-12(15)13(17)14(18)16-19-11-6-4-3-5-7-11/h3-7,10,12-13,17H,8-9,15H2,1-2H3,(H,16,18)/t12-,13+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against human methionine aminopeptidase-1				Bioorg Med Chem Lett 14: 865-8 (2004) Article DOI: 10.1016/j.bmcl.2003.12.031 BindingDB Entry DOI: 10.7270/Q2Z31Z3N
					More data for this Ligand-Target Pair