Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene A-4 hydrolase
(Cavia porcellus) | BDBM50266246
((R)-3-(4-isopropylbenzylthio)-2-((S)-3-mercapto-2-...)Show SMILES CC(C)c1ccc(CSC(C)(C)[C@H](NC(=O)[C@H](C)CS)C(O)=O)cc1 |r| Show InChI InChI=1S/C19H29NO3S2/c1-12(2)15-8-6-14(7-9-15)11-25-19(4,5)16(18(22)23)20-17(21)13(3)10-24/h6-9,12-13,16,24H,10-11H2,1-5H3,(H,20,21)(H,22,23)/t13-,16-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Santen Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 production |
Bioorg Med Chem Lett 19: 442-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.042
BindingDB Entry DOI: 10.7270/Q20K28FC |
More data for this
Ligand-Target Pair | |
Angiotensin-converting enzyme
(Homo sapiens (Human)) | BDBM50266246
((R)-3-(4-isopropylbenzylthio)-2-((S)-3-mercapto-2-...)Show SMILES CC(C)c1ccc(CSC(C)(C)[C@H](NC(=O)[C@H](C)CS)C(O)=O)cc1 |r| Show InChI InChI=1S/C19H29NO3S2/c1-12(2)15-8-6-14(7-9-15)11-25-19(4,5)16(18(22)23)20-17(21)13(3)10-24/h6-9,12-13,16,24H,10-11H2,1-5H3,(H,20,21)(H,22,23)/t13-,16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Santen Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of angiotensin-converting enzyme (unknown origin) in whole blood by HPLC |
Bioorg Med Chem Lett 19: 442-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.042
BindingDB Entry DOI: 10.7270/Q20K28FC |
More data for this
Ligand-Target Pair | |