Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM228180
(2-(3-Isopropyl-[1,2,4]triazol-1-yl)-1-{(R)-2-methy...)Show SMILES CC(C)c1ncn(CC(=O)N2C(C)CNCC2c2sc(cc2-c2cnc(nc2)C(F)(F)F)C(F)(F)F)n1 Show InChI InChI=1S/C22H23F6N7OS/c1-11(2)19-32-10-34(33-19)9-17(36)35-12(3)5-29-8-15(35)18-14(4-16(37-18)21(23,24)25)13-6-30-20(31-7-13)22(26,27)28/h4,6-7,10-12,15,29H,5,8-9H2,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | 7.4 | n/a |
IDORSIA PHARMACEUTICALS LTD.
US Patent
| Assay Description
The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the... |
US Patent US10047080 (2018)
BindingDB Entry DOI: 10.7270/Q2JQ130F |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM228180
(2-(3-Isopropyl-[1,2,4]triazol-1-yl)-1-{(R)-2-methy...)Show SMILES CC(C)c1ncn(CC(=O)N2C(C)CNCC2c2sc(cc2-c2cnc(nc2)C(F)(F)F)C(F)(F)F)n1 Show InChI InChI=1S/C22H23F6N7OS/c1-11(2)19-32-10-34(33-19)9-17(36)35-12(3)5-29-8-15(35)18-14(4-16(37-18)21(23,24)25)13-6-30-20(31-7-13)22(26,27)28/h4,6-7,10-12,15,29H,5,8-9H2,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 174 | n/a | n/a | n/a | n/a | n/a | n/a |
IDORSIA PHARMACEUTICALS LTD.
US Patent
| Assay Description
Stock solutions of test compounds are made up at a concentration of 10 mM in DMSO, and serially diluted in PBS containing 0.5% BSA to concentrations ... |
US Patent US10047080 (2018)
BindingDB Entry DOI: 10.7270/Q2JQ130F |
More data for this
Ligand-Target Pair | |