Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50188251
(2-(4-(4-((2-(2,4-dichlorophenoxy)ethyl)carbamoyl)-...)Show SMILES CC(C)c1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccc(CC(O)=O)cc1Cl Show InChI InChI=1S/C23H21Cl3N2O5/c1-12(2)22-20(23(31)27-7-8-32-18-6-4-14(24)11-17(18)26)21(28-33-22)15-5-3-13(9-16(15)25)10-19(29)30/h3-6,9,11-12H,7-8,10H2,1-2H3,(H,27,31)(H,29,30) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
| Assay Description Agonist activity at PPARgamma by transactivation assay |
Bioorg Med Chem Lett 16: 4376-80 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.055 BindingDB Entry DOI: 10.7270/Q2V987PC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50188251
(2-(4-(4-((2-(2,4-dichlorophenoxy)ethyl)carbamoyl)-...)Show SMILES CC(C)c1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccc(CC(O)=O)cc1Cl Show InChI InChI=1S/C23H21Cl3N2O5/c1-12(2)22-20(23(31)27-7-8-32-18-6-4-14(24)11-17(18)26)21(28-33-22)15-5-3-13(9-16(15)25)10-19(29)30/h3-6,9,11-12H,7-8,10H2,1-2H3,(H,27,31)(H,29,30) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 7.11E+3 | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
| Assay Description Agonist activity at PPARalpha by transactivation assay |
Bioorg Med Chem Lett 16: 4376-80 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.055 BindingDB Entry DOI: 10.7270/Q2V987PC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50188251
(2-(4-(4-((2-(2,4-dichlorophenoxy)ethyl)carbamoyl)-...)Show SMILES CC(C)c1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccc(CC(O)=O)cc1Cl Show InChI InChI=1S/C23H21Cl3N2O5/c1-12(2)22-20(23(31)27-7-8-32-18-6-4-14(24)11-17(18)26)21(28-33-22)15-5-3-13(9-16(15)25)10-19(29)30/h3-6,9,11-12H,7-8,10H2,1-2H3,(H,27,31)(H,29,30) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 90 | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
| Assay Description Agonist activity at PPARdelta by transactivation assay |
Bioorg Med Chem Lett 16: 4376-80 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.055 BindingDB Entry DOI: 10.7270/Q2V987PC |
More data for this Ligand-Target Pair | |