Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 270.3 BDBM50169347

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50169347 (6-(4-Fluoro-phenyl)-1-isopropyl-1,3-dihydro-benzoi...) Show SMILES CC(C)n1c2cc(ccc2[nH]c1=O)-c1ccc(F)cc1 Show InChI InChI=1S/C16H15FN2O/c1-10(2)19-15-9-12(5-8-14(15)18-16(19)20)11-3-6-13(17)7-4-11/h3-10H,1-2H3,(H,18,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	295	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assay				Bioorg Med Chem Lett 15: 3600-3 (2005) Article DOI: 10.1016/j.bmcl.2005.05.082 BindingDB Entry DOI: 10.7270/Q23J3CHG
					More data for this Ligand-Target Pair