Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acetyl-CoA carboxylase 2
(Homo sapiens (Human)) | BDBM152857
(US8993586, 35)Show SMILES CC(C)n1ncc2CC3(CCN(CC3)C(=O)C3=CC4N=C(N)NC4C=C3)NC(=O)c12 |c:26,t:17,20| Show InChI InChI=1S/C21H27N7O2/c1-12(2)28-17-14(11-23-28)10-21(26-18(17)29)5-7-27(8-6-21)19(30)13-3-4-15-16(9-13)25-20(22)24-15/h3-4,9,11-12,15-16H,5-8,10H2,1-2H3,(H,26,29)(H3,22,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description
Preparation of rhACC2. Human ACC2 inhibition was measured using purified recombinant human ACC2 (hrACC2). Briefly, a full length Cytomax clone of ACC... |
US Patent US8993586 (2015)
BindingDB Entry DOI: 10.7270/Q2N58K43 |
More data for this
Ligand-Target Pair | |
Acetyl-CoA carboxylase 1
(Homo sapiens (Human)) | BDBM152857
(US8993586, 35)Show SMILES CC(C)n1ncc2CC3(CCN(CC3)C(=O)C3=CC4N=C(N)NC4C=C3)NC(=O)c12 |c:26,t:17,20| Show InChI InChI=1S/C21H27N7O2/c1-12(2)28-17-14(11-23-28)10-21(26-18(17)29)5-7-27(8-6-21)19(30)13-3-4-15-16(9-13)25-20(22)24-15/h3-4,9,11-12,15-16H,5-8,10H2,1-2H3,(H,26,29)(H3,22,24,25) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 487 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Pfizer Inc.
US Patent
| Assay Description
Preparation of rhACC1. Two liters of SF9 cells, infected with recombinant baculovirus containing full length human ACC1 cDNA, were suspended in ice-c... |
US Patent US8993586 (2015)
BindingDB Entry DOI: 10.7270/Q2N58K43 |
More data for this
Ligand-Target Pair | |