Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Integrin alpha-2/beta-3
(Homo sapiens (Human)) | BDBM50354353
(CHEMBL1836348)Show SMILES CC(CC(O)=O)N1Cc2ccc(NC(=O)CCCC3CCNCC3)cc2C1=O Show InChI InChI=1S/C21H29N3O4/c1-14(11-20(26)27)24-13-16-5-6-17(12-18(16)21(24)28)23-19(25)4-2-3-15-7-9-22-10-8-15/h5-6,12,14-15,22H,2-4,7-11,13H2,1H3,(H,23,25)(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine
Curated by ChEMBL
| Assay Description
Displacement of FITC-labeled fibrinogen from alpha2beta3 in human platelets |
Bioorg Med Chem Lett 21: 5971-4 (2011)
Article DOI: 10.1016/j.bmcl.2011.07.063
BindingDB Entry DOI: 10.7270/Q26Q1XNS |
More data for this
Ligand-Target Pair | |
Integrin alpha-IIb/beta-3
(Homo sapiens (Human)) | BDBM50354353
(CHEMBL1836348)Show SMILES CC(CC(O)=O)N1Cc2ccc(NC(=O)CCCC3CCNCC3)cc2C1=O Show InChI InChI=1S/C21H29N3O4/c1-14(11-20(26)27)24-13-16-5-6-17(12-18(16)21(24)28)23-19(25)4-2-3-15-7-9-22-10-8-15/h5-6,12,14-15,22H,2-4,7-11,13H2,1H3,(H,23,25)(H,26,27) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine
Curated by ChEMBL
| Assay Description
Inhibition of FITC-labeled fibrinogen binding to integrin alpha2bbeta3 receptor in human platelets by flow cytometry |
Bioorg Med Chem 21: 4646-61 (2013)
Article DOI: 10.1016/j.bmc.2013.05.019
BindingDB Entry DOI: 10.7270/Q2Q81FGX |
More data for this
Ligand-Target Pair | |