Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM482430
(US10919852, Compound TABLE 1.129 | US11708326, Com...)Show SMILES CC(CO)(NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CC(O)C3)c2Cl)cc1OCc1cccnc1)C(O)=O |r| Show InChI InChI=1S/C38H41Cl2N3O7/c1-38(23-44,37(46)47)42-19-25-16-31(39)35(17-34(25)49-22-24-6-4-13-41-18-24)50-32-12-11-28-27(7-2-8-29(28)32)30-9-3-10-33(36(30)40)48-15-5-14-43-20-26(45)21-43/h2-4,6-10,13,16-18,26,32,42,44-45H,5,11-12,14-15,19-23H2,1H3,(H,46,47)/t32-,38?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22N56DJ |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1
(Homo sapiens) | BDBM482430
(US10919852, Compound TABLE 1.129 | US11708326, Com...)Show SMILES CC(CO)(NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CC(O)C3)c2Cl)cc1OCc1cccnc1)C(O)=O |r| Show InChI InChI=1S/C38H41Cl2N3O7/c1-38(23-44,37(46)47)42-19-25-16-31(39)35(17-34(25)49-22-24-6-4-13-41-18-24)50-32-12-11-28-27(7-2-8-29(28)32)30-9-3-10-33(36(30)40)48-15-5-14-43-20-26(45)21-43/h2-4,6-10,13,16-18,26,32,42,44-45H,5,11-12,14-15,19-23H2,1H3,(H,46,47)/t32-,38?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ChemoCentryx, Inc.
US Patent
| Assay Description
96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W... |
US Patent US10919852 (2021)
BindingDB Entry DOI: 10.7270/Q2RF5Z3R |
More data for this
Ligand-Target Pair | |