Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 378.4 BDBM50101557

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50101557 (1-[2-(4-Fluoro-phenyl)-1-methyl-ethyl]-1-methyl-3-...) Show SMILES CC(Cc1ccc(F)cc1)N(C)C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C23H23FN2O2/c1-17(16-18-8-10-19(24)11-9-18)26(2)23(27)25-20-12-14-22(15-13-20)28-21-6-4-3-5-7-21/h3-15,17H,16H2,1-2H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory activity tested against Human Neuropeptide Y2 Receptor.				J Med Chem 44: 2344-56 (2001) BindingDB Entry DOI: 10.7270/Q2DV1J56
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50101557 (1-[2-(4-Fluoro-phenyl)-1-methyl-ethyl]-1-methyl-3-...) Show SMILES CC(Cc1ccc(F)cc1)N(C)C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C23H23FN2O2/c1-17(16-18-8-10-19(24)11-9-18)26(2)23(27)25-20-12-14-22(15-13-20)28-21-6-4-3-5-7-21/h3-15,17H,16H2,1-2H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory activity tested against Human Neuropeptide Y1 Receptor.				J Med Chem 44: 2344-56 (2001) BindingDB Entry DOI: 10.7270/Q2DV1J56
					More data for this Ligand-Target Pair