Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 411.4 BDBM50125819

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-serine O-palmitoleoyltransferase porcupine (Homo sapiens (Human))	BDBM50125819 (CHEMBL3623895) Show SMILES CC(Oc1ccc(cc1)-c1ccnc(C)c1)C(=O)Nc1ccc(cn1)-c1cnccn1 Show InChI InChI=1S/C24H21N5O2/c1-16-13-19(9-10-26-16)18-3-6-21(7-4-18)31-17(2)24(30)29-23-8-5-20(14-28-23)22-15-25-11-12-27-22/h3-15,17H,1-2H3,(H,28,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of porcupine (unknown origin) expressed in mouse L Wnt3A cells co-cultured with TM3 cells harboring luciferase reporter gene assessed as r...				Bioorg Med Chem 23: 6855-68 (2015) Article DOI: 10.1016/j.bmc.2015.09.048 BindingDB Entry DOI: 10.7270/Q2J10500
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